DPSRU stated its journey with a DIPLOMA in Pharmacy course in 1964 at Kashmiri gate polytechnic and later it was transferred to PUSA Polytechnic building with induction of B.Pharmacy course with 20 students in 1972, later on in 1979 it has been shifted to the present lush green campus of 10.5 acres at Pushp Vihar, subsequently in 1978 M.Pharmacy  was started in two streams i.e. Pharmacology, Pharmaceutics, where in 1982 Hospital Pharmacy , in 1996 Quality Assurance, in 2007 Pharmaceutical Chemistry and Clinical Pharmacy and in 2008 Pharmaceutical Management  were also added up as strames of M.Pharmacy. M.Pharmacy in Herbal Drug Technology is likely to be started in academic year 2009-2010. Ph.D. programme under stipendiary category (14000 + hostel/HRA) were started in year 2006.

Apart from this DIPSAR conduct M.Pharm and PhD courses for Teachers of Pharmacy colleges under Quality Improvement Programme. Medicine and Antidote information centre “MAPIC” was inaugurated in 2003 by Hon’ble Chief Minister Smt. Sheila Dixit, for disbursement of the information about any drug, its side effects, uses contraindications toxicity or first aid remedy for accidental consumption of poisons. It is the only Institute of Pharmacy in India where the faculty members are selected through Union Public Service Commission (UPSC), Govt. of India. It is funded by Govt. of NCT of Delhi. Moreover now DIPSAR is equipped with 10 state of art research l laboratories, gymnasium, Swimming Pool, Guest House, Sports Complex, World Class  Hostels, State of art animal house with clean and dirty corridors etc.

The Institute has been identified by AICTE as the Host Institution for National Doctoral Fellowship Scheme (NDF) and early Faculty induction Programme (EFIP).

In addition work on 8+1 storey P.G block at present location (Pushp Vihar) has already begun after approval from different authorities like Airport authorities, MCD, Fire authorities, Urban art authorities.